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Article

GSTP1 I105V polymorphism and susceptibility to colorectal cancer in Kashmiri population.

DNA and cell biology - 1 Jan 2012

Sameer A Syed, Qadri Qurteeba, Siddiqi Mushtaq A

Abstract excerpt

The glutathione S-transferase (GST) enzyme encoded by the GSTP1 gene is one of the critical enzymes involved in detoxification of carcinogens. The substitution of isoleucine to valine residue at position 105 of the GSTP1 protein results in decreased enzyme activity and hence less capability of effective detoxification. Hence, we investigated the role of GSTP1 I105V polymorphism in modulating the risk of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21711092
DOI: 10.1089/dna.2011.1297

Genes

GSTP1

Variants

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GSTP1 I105V polymorphism and susceptibility to colorectal cancer in Kashmiri population.PMID 21711092Read ↗

GSTP1 Ile105Val polymorphism and colorectal cancer risk: an updated analysis.Semantic proximity Read ↗

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Associations of the glutathione S-transferase P1 Ile105Val genetic polymorphism with gynecological cancer susceptibility: a meta-analysis.Semantic proximity Read ↗

The GSTP1 Ile105Val polymorphism is not associated with susceptibility to colorectal cancer.Semantic proximity Read ↗

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