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Article

Identification of genetic loci underlying the phenotypic constructs of autism spectrum disorders.

Journal of the American Academy of Child and Adolescent Psychiatry - 1 Jul 2011

Liu Xiao-Qing, Georgiades Stelios, Duku Eric, Thompson Ann, Devlin Bernie, Cook Edwin H, Wijsman Ellen M, Paterson Andrew D, Szatmari Peter

Abstract excerpt

OBJECTIVE: To investigate the underlying phenotypic constructs in autism spectrum disorders (ASD) and to identify genetic loci that are linked to these empirically derived factors. METHOD: Exploratory factor analysis was applied to two datasets with 28 selected Autism Diagnostic Interview-Revised (ADI-R) algorithm items. The first dataset was from the Autism Genome Project (AGP) phase I (1,236 ASD subjects from...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21703496
DOI: 10.1016/j.jaac.2011.05.002
PMCID: PMC3593812

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