Article
Transcriptome Profiling of Whole Blood Cells Identifies PLEK2 and C1QB in Human Melanoma
15 Jun 2011
Abstract excerpt
BACKGROUND: Developing analytical methodologies to identify biomarkers in easily accessible body fluids is highly valuable for the early diagnosis and management of cancer patients. Peripheral whole blood is a "nucleic acid-rich" and "inflammatory cell-rich" information reservoir and represents systemic processes altered by the presence of cancer cells. METHODOLOGY/PRINCIPAL FINDINGS: We conducted transcriptome...
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