Article
Extensive horizontal gene transfer in ureaplasmas from humans questions the utility of serotyping for diagnostic purposes.
Journal of clinical microbiology - 1 Aug 2011
Xiao Li, Paralanov Vanya, Glass John I, Duffy Lynn B, Robertson Janet A, Cassell Gail H, Chen Yuying, Waites Ken B
Abstract excerpt
Ureaplasma parvum and Ureaplasma urealyticum are sexually transmitted, opportunistic pathogens of the human urogenital tract. There are 14 known serovars distributed between the two species. For decades, it has been postulated based upon limited data that virulence is related to serotype specificity. The results were often inconclusive due to the small sample size and extensive cross-reactivity between certain...
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