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Article

Amyloid-β protein precursor family members: a review from homology to biological function.

Journal of Alzheimer's disease : JAD - 1 Jan 2011

Huang Han-Chang, Jiang Zhao-Feng

Abstract excerpt

Alzheimer's disease (AD) is one of the most common forms of neurodegenerative disease. Amyloid-β peptide (Aβ) is the most crucial molecule related to the pathological development of AD. Amyloid-β protein precursor (AβPP) is one of AβPP family members with conserved type I transmembrane. The genetic mutations of AβPP and the abnormity of its post-transcription and proteolytic processing contribute to the elevation...

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Identifiers

PMID: 21694452
DOI: 10.3233/JAD-2011-110335

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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