Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The unusual spectrum of mutations induced by hybrid dysgenesis at the Triplo-lethal locus of Drosophila melanogaster.

Genetics - 1 Aug 1990

Dorer D R, Christensen A C

Abstract excerpt

The Triplo-lethal locus (Tpl) is unique in its dosage sensitivity; no other locus in Drosophila has been identified that is lethal when present in three doses. Tpl is also haplo-lethal, and its function is still a mystery. Previous workers have found it nearly impossible to mutationally inactive Tpl other than by completely deleting the chromosomal region in which Tpl resides (83DE). We have utilized P-M hybrid...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Chromosome Banding
Share to Crosses, Genetic

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA Transposable Elements

Share to Drosophila melanogaster

Share to Genes, Lethal

Share to Mutation

Source

Open in PubMed Open full text

Identifiers

PMID: 2168850
DOI: 10.1093/genetics/125.4.795
PMCID: PMC1204105

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The unusual spectrum of mutations induced by hybrid dysgenesis at the Triplo-lethal locus of Drosophila melanogaster.PMID 2168850Read ↗

A novel RNA helicase gene tightly linked to the Triplo-lethal locus of Drosophila.Semantic proximity Read ↗

Phenotype of the Triplo-lethal locus of Drosophila melanogaster and its suppression by hyperoxia.Semantic proximity Read ↗

Suppression of a lethal trisomic phenotype in Drosophila melanogaster by increased dosage of an unlinked locus.Semantic proximity Read ↗

Phenotypic and genomic analysis of <i>P</i> elements in natural populations of <i>Drosophila melanogaster</i>Semantic proximity Read ↗

Drosophila melanogaster P transposable elements: mechanisms of transposition and regulation.Semantic proximity Read ↗

Repression of hybrid dysgenesis in Drosophila melanogaster by combinations of telomeric P-element reporters and naturally occurring P elements.Semantic proximity Read ↗

High-frequency P element loss in Drosophila is homolog dependent.Semantic proximity Read ↗

The P-element-induced silencing effect of KP transposons is dose dependent in Drosophila melanogaster.Semantic proximity Read ↗

Genetic and molecular analysis of repression in the P-M system of hybrid dysgenesis in Drosophila melanogaster.Semantic proximity Read ↗

Genetic and developmental analysis of a temperature-sensitive minute mutation of Drosophila melanogaster.Semantic proximity Read ↗

Stress and haploadaptability of the lgl tumor suppressor: population and genetic studies on Drosophila.Semantic proximity Read ↗

Lethal mutations induced by DNA in Drosophila melanogaster.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.