The unusual spectrum of mutations induced by hybrid dysgenesis at the Triplo-lethal locus of Drosophila melanogaster.

doi:10.1093/genetics/125.4.795

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Article

The unusual spectrum of mutations induced by hybrid dysgenesis at the Triplo-lethal locus of Drosophila melanogaster.

Genetics - 1 Aug 1990

Dorer D R, Christensen A C

Abstract excerpt

The Triplo-lethal locus (Tpl) is unique in its dosage sensitivity; no other locus in Drosophila has been identified that is lethal when present in three doses. Tpl is also haplo-lethal, and its function is still a mystery. Previous workers have found it nearly impossible to mutationally inactive...

Topics

Alleles
Animals
Chromosome Banding
Crosses, Genetic
DNA Transposable Elements
Drosophila melanogaster
Female
Genes, Lethal
Male
Mutation

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