Article
Multiple chromosomal monosomies are characteristic of giant cell ependymoma.
Human pathology - 1 Dec 2011
Dahlback Hanne-Sofie S, Brandal Petter, Krossnes Bård K, Fric Radek, Meling Torstein R, Meza-Zepeda Leonardo A, Danielsen Håvard E, Heim Sverre
Abstract excerpt
Giant cell ependymoma, a rare ependymoma subtype, was recently recognized as a separate diagnostic entity with variations both in malignant potential and course of disease. We analyzed the first supratentorial giant cell ependymoma using G-band karyotyping, DNA ploidy analysis, and array comparative genomic hybridization. The tumor was hypodiploid, and the karyotype showed multiple monosomies. This novel...
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