Article
Complex cytogenetic abnormalities including telomeric associations and MEN1 mutation in a pediatric ependymoma.
Cancer genetics and cytogenetics - 15 Oct 2002
Urioste M, Martínez-Ramírez A, Cigudosa J C, Colmenero I, Madero L, Robledo M, Martínez-Delgado B, Benítez J
Abstract excerpt
Ependymomas are neuroectodermal tumors of the brain and spinal cord. Some recurrent cytogenetic aberrations have been reported in these tumors, including alterations involving chromosomes 22, 6, and 11. However, consistent molecular alterations have not been identified in ependymal tumors. We studied a recurrent ependymoma in a 3-year-old patient by standard cytogenetic and molecular analysis of TP53 and MEN1...
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