Article
Different β-amyloid oligomer assemblies in Alzheimer brains correlate with age of disease onset and impaired cholinergic activity.
Neurobiology of aging - 1 Apr 2012
Bao Fuxiang, Wicklund Linn, Lacor Pascale N, Klein William L, Nordberg Agneta, Marutle Amelia
Abstract excerpt
In this study, we examined the relationship between various β-amyloid (Aβ) oligomer assemblies in autopsy brain with the levels of fibrillar Aβ and cholinergic synaptic function. Brain tissues obtained from the frontal cortex of 14 Alzheimer's disease (AD) patients grouped into early-onset AD (EO...
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