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Deep Sequencing of Patient Genomes for Disease Diagnosis: When Will It Become Routine?

15 Jun 2011

Abstract excerpt

Next-generation sequencing technologies have greatly lowered the cost of whole-genome sequencing (WGS) and related approaches. Thus, comprehensive sequencing for diagnostic purposes may clear this financial hurdle in the near future. The report by Bainbridge and colleagues in this issue of Science Translational Medicine illustrates the diagnostic power of WGS. In this Perspective, we discuss whether and how...

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PMID: 21677196
DOI: 10.1126/scitranslmed.3002695

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