Article
Role of fibroblast growth factor (FGF) signaling in the neuroendocrine control of human reproduction.
Molecular and cellular endocrinology - 22 Oct 2011
Miraoui Hichem, Dwyer Andrew, Pitteloud Nelly
Abstract excerpt
Fibroblast growth factor (FGF) signaling is critical for a broad range of developmental processes. In 2003, Fibroblast growth factor receptor 1 (FGFR1) was discovered as a novel locus causing both forms of isolate GnRH Deficiency, Kallmann syndrome [KS with anosmia] and normosmic idiopathic hypogonadotropic hypogonadism [nIHH] eventually accounting for approximately 10% of gonadotropin-releasing hormone (GnRH)...
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