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Article

Role of gut microbiota in graft-versus-host disease

12 Jun 2011

Abstract excerpt

Our understanding of graft-versus-host disease (GVHD) has mostly focused on the role of adaptive immunity in mediating host-recipient genetic disparity in the proinflammatory milieu. These experimental models rarely address the unique biology of GVHD whereby it targets mainly epithelial compartments of the intestine, skin, and liver. Recent discoveries of the role of the microbiota in health and disease have...

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PMID: 21663498
DOI: 10.3109/10428194.2011.580476

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