[Biclonal or biphenotypic chronic lymphotic leukemia? An answer brought by the treatment].

doi:10.1684/abc.2011.0575

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Article

[Biclonal or biphenotypic chronic lymphotic leukemia? An answer brought by the treatment].

Annales de biologie clinique - 1 Jan 2000

Acker Céline, Staal Anne, Aumont Cédric, Didion Jacqueline, Dorvaux Véronique, Rio Yves, Latger-Cannard Véronique

Abstract excerpt

A 51-years-old patient with polyadenopathies presents a non monotypic chronic lymphocytic leukemia (CLL): lymphocytes B CD5+, CD23+, CD22-,CD79b dim, FMC7- express κ (71%) and λ (21%) light chains without coexpression. The caryotype shows two clones with one in evolution. Lymphoid clonality analysis by PCR (polymerase chain reaction) of the heavy and light chains genes of immunoglobulins shows two monoclonal...

Topics

Drug Resistance, Neoplasm
Humans
Leukemia, Lymphocytic, Chronic, B-Cell
Male
Middle Aged
Phenotype

Source

Open in PubMed

Identifiers

PMID: 21659049
DOI: 10.1684/abc.2011.0575

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