Article
Comparison of molecular diagnostic methods for the detection of Acanthamoeba spp. from clinical specimens submitted for keratitis.
Diagnostic microbiology and infectious disease - 1 Aug 2011
Khairnar Krishna, Tamber Gurdip S, Ralevski Filip, Pillai Dylan R
Abstract excerpt
Acanthamoeba spp. are responsible for a significant annual number of keratitis (AK) cases leading to vision-threatening disease worldwide. Current methods rely on direct examination of specimens by microscopy and/or culture. The former lacks sensitivity and the latter suffers from a poor turnaround time. We undertook a comparison of all published molecular methods, evaluating performance characteristics such as...
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