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Article

The Legionella pneumophila major secretory protein, a protease, is not required for intracellular growth or cell killing.

Infection and immunity - 1 Aug 1990

Szeto L, Shuman H A

Abstract excerpt

The Legionella pneumophila major secretory protein (Msp) is a Zn2+ metalloprotease whose function in pathogenesis is unknown. The structural gene for the Msp protease, mspA, was isolated from an L. pneumophila genomic library. In Escherichia coli which contain plasmids with the mspA gene, Msp protein and activity are found in the periplasmic space and the cytoplasm. Transposon mutagenesis with Tn9 of an...

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Identifiers

PMID: 2164510
DOI: 10.1128/iai.58.8.2585-2592.1990
PMCID: PMC258859

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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