Article
[Association between single nucleotide polymorphisms of 5'-untranslated region of GPx4 gene and male infertility].
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics - 1 Jun 2011
Liu Shu-yuan, Zhang Chang-jun, Si Xiao-min, Yao Yu-feng, Shi Lei, Ke Jin-kun, Yu Liang, Shi Li, Yang Zhao-qin, Huang Xiao-qin, Sun Hao, Chu Jia-you
Abstract excerpt
OBJECTIVE: To study the association between the single nucleotide polymorphisms (SNPs) of the 5'-untranslated region (5'-UTR) of phospholipid hydroperoxide glutathione peroxidase (GPx4 or PHGPx) gene and oligo- or asthenozoospermic male infertility. METHODS: The 5'-UTR region of the GPx4 gene was amplified from infertile men and controls using the polymerase chain reaction and was analyzed for polymorphisms by...
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