Article
Human neutrophil collagenase. A distinct gene product with homology to other matrix metalloproteinases.
1 Jul 1990
Abstract excerpt
We have identified and sequenced a cDNA encoding human neutrophil collagenase from a lambda gt11 cDNA library constructed from mRNA extracted from the peripheral leukocytes of a patient with chronic granulocytic leukemia. The library was screened with an oligonucleotide probe constructed from the putative zinc-binding region of fibroblast collagenase. Eleven positive clones were identified, of which the one...
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