Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genomic microdeletions associated with epilepsy: not a contraindication to resective surgery.

Epilepsia - 1 Aug 2011

Catarino Claudia B, Kasperavičiūtė Dalia, Thom Maria, Cavalleri Gianpiero L, Martinian Lillian, Heinzen Erin L, Dorn Thomas, Grunwald Thomas, Chaila Elijah, Depondt Chantal, Krämer Günter, Delanty Norman, Goldstein David B, Sisodiya Sanjay M

Abstract excerpt

PURPOSE: Several recent reports of genomic microdeletions in epilepsy will generate further research; discovery of more microdeletions and other important classes of variants may follow. Detection of such genetic abnormalities in patients being evaluated for surgical treatment might raise concern that a genetic defect, possibly widely expressed in the brain, will affect surgical outcome. METHODS: A reevaluation...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosome Deletion
Share to Contraindications

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Copy Number Variations

Share to Epilepsy, Temporal Lobe

Share to Follow-Up Studies

Share to Hippocampus

Share to Neurosurgical Procedures

Share to Sclerosis

Source

Open in PubMed Open full text

Identifiers

PMID: 21635232
DOI: 10.1111/j.1528-1167.2011.03087.x
PMCID: PMC3399084

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genomic microdeletions associated with epilepsy: not a contraindication to resective surgery.PMID 21635232Read ↗

Heterogeneous Contribution of Microdeletions in the Development of Common Generalized and Focal epilepsiesSemantic proximity Read ↗

Heterogeneous contribution of microdeletions in the development of common generalised and focal epilepsiesSemantic proximity Read ↗

Array comparative genomic hybridization: results from an adult population with drug-resistant epilepsy and co-morbidities.Semantic proximity Read ↗

Multifocal Rosette-forming Glioneuronal Tumor-like Low-Grade Glioneuronal Tumor with Dysembryoplastic Neuroepithelial Tumor Features Associated with Drug-Resistant Epilepsy: A Case Report and Literature ReviewSemantic proximity Read ↗

Focal cortical dysplasia: a review of pathological features, genetics, and surgical outcome.Semantic proximity Read ↗

Recurrent microdeletions at 15q11.2 and 16p13.11 predispose to idiopathic generalized epilepsies.Semantic proximity Read ↗

Contribution of Somatic Ras/Raf/Mitogen-Activated Protein Kinase Variants in the Hippocampus in Drug-Resistant Mesial Temporal Lobe EpilepsySemantic proximity Read ↗

Neuropathology of 16p13.11 deletion in epilepsy.Semantic proximity Read ↗

Losing neurons: selective vulnerability and mesial temporal sclerosis.Semantic proximity Read ↗

Poor reliability and reproducibility of PCR-based testing of O6-methylguanine-DNA methyltransferase gene (MGMT) promoter methylation status in formalin-fixed and paraffin-embedded neurosurgical biopsy specimensSemantic proximity Read ↗

Major vault protein, a marker of drug resistance, is upregulated in refractory epilepsy.Semantic proximity Read ↗

Clinical and histopathological outcomes in patients with SCN1A mutations undergoing surgery for epilepsy.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.