Article
Renin-angiotensin-aldosterone system genes and nonarteritic anterior ischemic optic neuropathy.
Molecular vision - 1 Jan 2011
Markoula Sofia, Giannopoulos Sotirios, Asproudis Ioannis, Kostoulas Charilaos, Nikas Alexios, Bagli Eleni, Kyritsis Athanassios P, Georgiou Ioannis
Abstract excerpt
PURPOSE: Recent literature suggests a genetic component for non-arteritic anterior ischemic optic neuropathy (NAION). We examined the association of the insertion/deletion (I/D) polymorphism of the angiotensin-converting enzyme gene, of the M235T polymorphism of the angiotensinogen gene, and of the A1166C polymorphism of the angiotensin II type 1 receptor gene with NAION. METHODS: Forty-seven patients with NAION...
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