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Article

Endothelial nitric oxide synthase gene polymorphisms in non-arteritic anterior ischemic optic neuropathy.

Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie - 1 Feb 2007

Sakai Tsutomu, Shikishima Keigo, Matsushima Masato, Kitahara Kenji

Abstract excerpt

BACKGROUND: To examine the association between the polymorphisms of the endothelial nitric oxide synthase (eNOS) gene and the occurrence of non-arteritic anterior ischemic optic neuropathy (NAION). METHODS: We studied 15 patients with NAION (mean age, 62 years; 60% male). We investigated two polymorphisms of the eNOS gene, Glu298Asp polymorphism of exon 7 and T(-786)C polymorphism of the promoter region. The...

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PMID: 16633797
DOI: 10.1007/s00417-005-0245-7

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