Article
Increased sleep spindle activity in patients with Costello syndrome (HRAS gene mutation).
Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society - 1 Jun 2011
Della Marca Giacomo, Leoni Chiara, Dittoni Serena, Battaglia Domenica, Losurdo Anna, Testani Elisa, Colicchio Salvatore, Gnoni Valentina, Gambardella Maria L, Mariotti Paolo, Alfieri Paolo, Tartaglia Marco, Zampino Giuseppe
Abstract excerpt
Costello syndrome is a congenital disorder because of HRAS gene mutation, frequently associated with neurologic impairment and sleep disorders. The aims of the study were to evaluate the sleep EEG, and particularly the sleep spindles, in a population of patients with Costello syndrome and to compare them with those characterizing unaffected subjects. Eleven subjects (5 men and 6 women) with Costello syndrome were...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.