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Article

Abnormal sleep physiology in children with 15q11.2-13.1 duplication (Dup15q) syndrome

3 Aug 2021

Abstract excerpt

Abstract Background Sleep disturbances in autism spectrum disorder (ASD) represent a common and vexing comorbidity. Clinical heterogeneity amongst these warrants studies of the mechanisms associated with specific genetic etiologies. Duplications of 15q11.2-13.1 (Dup15q syndrome) are highly penetrant for neurodevelopmental disorders (NDDs) such as intellectual disability and ASD, as well as sleep disturbances....

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PMID: 34344470
DOI: 10.1186/s13229-021-00460-8

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