Article
[Relationship between genetic polymorphism in microRNAs precursor and genetic predisposition of hepatocellular carcinoma].
Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine] - 1 Mar 2011
Zhang Xin-wei, Pan Shan-dong, Feng Yao-liang, Liu Ji-bin, Dong Jing, Zhang Yi-xin, Chen Jian-guo, Hu Zhi-bin, Shen Hong-bing
Abstract excerpt
OBJECTIVE: To investigate the relationship between genetic polymorphism in microRNAs (miRNAs) precursor and genetic predisposition of hepatocellular carcinoma (HCC) in Chinese population. METHODS: A case-control study including 963 HCC cases and 829 HBsAg positive controls and 852 HBsAg negative controls was conducted. hsa-mir-146a rs2910164 C→G and hsa-mir-196-a2 rs11614913 T→C were selected, where the genotypes...
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