Genetic dissection of late-life fertility in Caenorhabditis elegans.

doi:10.1093/gerona/glr089

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Article

Genetic dissection of late-life fertility in Caenorhabditis elegans.

The journals of gerontology. Series A, Biological sciences and medical sciences - 1 Aug 2011

Mendenhall Alexander R, Wu Deqing, Park Sang-Kyu, Cypser James R, Tedesco Patricia M, Link Christopher D, Phillips Patrick C, Johnson Thomas E

Abstract excerpt

The large post-reproductive life span reported for the free-living hermaphroditic nematode, Caenorhabditis elegans, which lives for about 10 days after its 5-day period of self-reproduction, seems at odds with evolutionary theory. Species with long post-reproductive life spans such as mammals are sometimes explained by a need for parental care or transfer of information. This does not seem a suitable explanation...

Topics

Aging
Animals
Caenorhabditis elegans
Diet
Fertility
Germ Cells
Gonads
Longevity
Male
Mutation
Reproduction
Transcription Factors

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Identifiers

PMID: 21622982
DOI: 10.1093/gerona/glr089
PMCID: PMC3148761

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