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Article

Host defense pathways: role of redundancy and compensation in infectious disease phenotypes.

Immunity - 27 May 2011

Nish Simone, Medzhitov Ruslan

Abstract excerpt

Innate host defense pathways consist of microbial sensors, their signaling pathways, and the antimicrobial effector mechanisms. Several classes of host defense pathways are currently known, each comprising several pattern-recognition receptors that detect different types of pathogens. These pathways interact with one another in a variety of ways that can be categorized into cooperation, complementation, and...

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Identifiers

PMID: 21616433
DOI: 10.1016/j.immuni.2011.05.009
PMCID: PMC3143490

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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