Article
Validation of a cost-efficient multi-purpose SNP panel for disease based research.
PloS one - 1 Jan 2011
Hou Liping, Phillips Christopher, Azaro Marco, Brzustowicz Linda M, Bartlett Christopher W
Abstract excerpt
BACKGROUND: Here we present convergent methodologies using theoretical calculations, empirical assessment on in-house and publicly available datasets as well as in silico simulations, that validate a panel of SNPs for a variety of necessary tasks in human genetics disease research before resources are committed to larger-scale genotyping studies on those samples. While large-scale well-funded human genetic...
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