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Article

Hypoxic mitochondria: accomplices in resistance.

Bulletin du cancer - 1 May 2011

Mazure N M, Brahimi-Horn M C, Pouysségur J

Abstract excerpt

Mitochondria originated from a distant ancestor: the α-proteobacteria. They evolved over millions of years in a symbiotic relationship in eukaryotic cells by favoring consumption of oxygen by the electron transport chain with production of ATP. Contemporary mitochondria still play a crucial role in providing energy but also in apoptosis. Because of this symbiotic relationship and their pivotal function,...

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Identifiers

PMID: 21609892
DOI: 10.1684/bdc.2011.1360

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