Article
Increased Müller cell de-differentiation after grafting of retinal stem cell in the sub-retinal space of Royal College of Surgeons rats.
Tissue engineering. Part A - 1 Oct 2011
Tian Chunyu, Zhao Tongtao, Zeng Yuxiao, Yin Zheng Qin
Abstract excerpt
In several vertebrate classes, the Müller glia are capable of de-differentiating, proliferating, and acquiring a progenitor-like state in response to acute retinal injury or in response to exogenous growth factors. Our previous study has shown that Müller cells can be activated and de-differentiated into retinal progenitors during Royal College of Surgeons (RCS) rats' degeneration, although the limited...
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