Article
MicroRNA based immunoevasion mechanism of human polyomaviruses
1 Jul 2011
Abstract excerpt
Since miRNAs are considered non-immunogenic, it was not too surprising to discover that some herpesviruses, which are masters of immune evasion, developed their own unique miRNAs to escape immune elimination. In this point of view we discuss our recent findings in which we demonstrate that two polyomaviruses, JC and BK, use an identical miRNA to escape immune attack. This identical miRNA targets the...
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