Article
Variation in antibiotic-induced microbial recolonization impacts on the host metabolic phenotypes of rats.
Journal of proteome research - 5 Aug 2011
Swann Jonathan R, Tuohy Kieran M, Lindfors Peter, Brown Duncan T, Gibson Glenn R, Wilson Ian D, Sidaway James, Nicholson Jeremy K, Holmes Elaine
Abstract excerpt
The interaction between the gut microbiota and their mammalian host is known to have far-reaching consequences with respect to metabolism and health. We investigated the effects of eight days of oral antibiotic exposure (penicillin and streptomycin sulfate) on gut microbial composition and host metabolic phenotype in male Han-Wistar rats (n = 6) compared to matched controls. Early recolonization was assessed in a...
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