Article
Autonomous transposition of gypsy mobile elements and genetic instability in Drosophila melanogaster.
Molecular & general genetics : MGG - 1 Nov 1990
Kim A I, Belyaeva E S, Aslanian M M
Abstract excerpt
The laboratory mutator strain (MS) of Drosophila melanogaster is characterized by an elevated frequency of spontaneous mutation (10(-3)-10(-4). Mutations occur in both sexes at premeiotic stages of germ cell development. The increased mutability is a characteristic feature of MS itself, since it appears in the absence of outcrossing. Most of the mutations arising in this strain are unstable: reversions to wild...
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