Article
Phenotypic and differentiation stability of human embryonic stem cell-derived osteoblasts.
Cells, tissues, organs - 1 Jan 2011
Arpornmaeklong Premjit, Pressler Michael J, Krebsbach Paul H
Abstract excerpt
PURPOSE: To ensure the efficiency and safety of transplanted human embryonic stem cell (hESC)-derived osteoblast-like cells (hESC-OS) for bone regeneration, this study was designed to determine the effects of continuous cell expansion on the osteoblastic differentiation stability, pluripotency, and tumorigenic potential of long-term expanded hESC-OS. METHODS: hESCs manually harvested as cell aggregates or...
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