Article
Morphology in Ki-1(CD30)-positive non-Hodgkin's lymphoma is correlated with clinical features and the presence of a unique chromosomal abnormality, t(2;5)(p23;q35).
The American journal of surgical pathology - 1 Apr 1990
Bitter M A, Franklin W A, Larson R A, McKeithan T W, Rubin C M, Le Beau M M, Stephens J K, Vardiman J W
Abstract excerpt
Ten patients with strongly Ki-1(CD30)-positive non-Hodgkin's lymphoma (NHL) were identified at our institution during the past 5 years. Based on morphology, the lymphomas of five of these patients were classified as anaplastic large-cell lymphoma (ALCL); the lymphomas of four patients lacked the morphologic features of ALCL (non-ALCL); and the lymphoma of one patient was unclassifiable. Significant clinical and...
Topics
- Antigens, CD
- Antigens, Differentiation
- Antigens, Neoplasm
- Cell Division
- Chromosome Aberrations
- Chromosome Disorders
- Humans
- Karyotyping
- Ki-1 Antigen
- Lymphoma, Non-Hodgkin