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AN ESSENTIAL CIS-ACTING ELEMENT OF THE LCK-3' PROMOTER REGULATES THE EXPRESSION OF P56(LCK) IN METASTATIC COLORECTAL-CANCER CELLS

1 Aug 1993

Abstract excerpt

Detection of lck-specific transcripts has been discussed as a marker for metastasis of epithelial tumor cells. Since it is known that lck expression is regulated post-transcriptionally, it was fundamental to us to identify lck in human colorectal cancer cell lines also at the protein level. Subsequently, RT-PCR was used to confirm that lck-producing colorectal cancer cell lines contain mature transcripts...

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PMID: 21573376
DOI: 10.3892/ijo.3.2.369

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