Article
CCR2-64I gene polymorphism increase susceptibility to oral cancer.
Oral oncology - 1 Jul 2011
Chen Mu-Kuan, Yeh Kun-Tu, Chiou Hui-Ling, Lin Chiao-Wen, Chung Tsung-Te, Yang Shun-Fa
Abstract excerpt
The purpose of this study was to investigate the impact of MCP-1 and its receptor CCR2 gene polymorphisms on the susceptibility and clinicopathological characteristics of oral cancer, as well as the synergistic effect between these gene polymorphisms and well-known risk factors including alcohol, tobacco, and areca consumptions. Using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP)...
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