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Clinical implementation of whole-genome array CGH as a first-tier test in 5080 pre and postnatal cases

9 May 2011

Abstract excerpt

BACKGROUND: Array comparative genomic hybridization (CGH) is currently the most powerful method for detecting chromosomal alterations in pre and postnatal clinical cases. In this study, we developed a BAC based array CGH analysis platform for detecting whole genome DNA copy number changes including specific micro deletion and duplication chromosomal disorders. Additionally, we report our experience with the...

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PMID: 21549014
DOI: 10.1186/1755-8166-4-12

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