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Article

The early programming of metabolic health: is epigenetic setting the missing link?

The American journal of clinical nutrition - 1 Dec 2011

Sebert Sylvain, Sharkey Don, Budge Helen, Symonds Michael E

Abstract excerpt

Adult health is dependent, in part, on maternal nutrition and growth during early life, which may independently affect insulin sensitivity, body composition, and overall energy homeostasis. Since the publication of the "thrifty phenotype hypothesis" by Hales and Barker (Diabetologia 1992;35:595-601), animal experiments have focused on establishing the mechanisms involved, which include changes in fetal cortisol,...

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Identifiers

PMID: 21543542
DOI: 10.3945/ajcn.110.001040

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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