Article
[Relationship of single-nucleotide polymorphism rs11562975 in thermo-sensitive ion channel TRPM8 gene with human sensitivity to cold and menthol].
Fiziologiia cheloveka - 1 Jan 2000
Kozyreva T V, Tkachenko E Ia, Potapova T A, Romashchenko A G, Voevoda M I
Abstract excerpt
The examination of people belonging to the Russian ethnic group revealed that 20.3% of subjects had heterozygous genotype, containing the C-allele in single nucleotide polymorphism rs11562975, located in exon 7 of the gene encoding the temperature-sensitive ion channel TRPM8. Functional differences, associated with sensitivity to cold and menthol were identified between subjects with different genotypes of the...
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