Identification of microRNA expression patterns in cutaneous and uveal melanoma cell lines.

Abstract excerpt

AIMS AND BACKGROUND: microRNA (miRNA)-mediated epigenetic regulation of tumor suppressor genes and oncogenes has been shown to play a central role in melanomagenesis. Here, we focused on the identification of miRNA signatures in the cutaneous melanoma cell line G361 and the uveal melanoma cell line OCM-1. METHODS AND STUDY DESIGN: We carried out genome-wide miRNA expression profiling using a human miRNA...

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