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Article

The champions' mitochondria: is it genetically determined? A review on mitochondrial DNA and elite athletic performance

4 May 2011

Abstract excerpt

Aerobic ATP generation by the mitochondrial respiratory oxidative phosphorylation system (OXPHOS) is a vital metabolic process for endurance exercise. Notably, mitochondrial DNA (mtDNA) codifies 13 of the 83 polypeptides implied in the respiratory chain. As such, there is a strong rationale for identifying an association between mtDNA variants and "aerobic" (endurance) exercise phenotypes. The aim of this review...

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PMID: 21540298
DOI: 10.1152/physiolgenomics.00029.2011

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