Article
Diagnosis of Whipple's disease using molecular biology techniques.
Revista espanola de enfermedades digestivas - 1 Apr 2011
Cosme Ángel, Ojeda Evelia, Muñagorri Ana I, Gaminde Eduardo, Bujanda Luis, Larzabal Mikel, Gil Inés
Abstract excerpt
The diagnosis of Whipple's disease (WD) is based on the existence of clinical signs and symptoms compatible with the disease and in the presence of PAS-positive diastase-resistant granules in the macrophages of the small intestine. If there is suspicion of the disease but no histological findings or only isolated extraintestinal manifestations, species-specific PCR using different sequences of the T. whippleii...
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