Article
Diabetes and breast cancer among women with BRCA1 and BRCA2 mutations.
Cancer - 1 May 2011
Bordeleau Louise, Lipscombe Lorraine, Lubinski Jan, Ghadirian Parviz, Foulkes William D, Neuhausen Susan, Ainsworth Peter, Pollak Michael, Sun Ping, Narod Steven A
Abstract excerpt
BACKGROUND: Hyperinsulinemia and the metabolic syndrome are both risk factors for breast cancer. It is not clear if diabetes is associated with the risk of breast cancer in women with a BRCA1 or BRCA2 mutation. METHODS: The authors reviewed the medical histories of 6052 women with a BRCA1 or BRCA2 mutation, half of whom had been diagnosed with breast cancer. They estimated the odds ratio for breast cancer, given...
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