Article
Analysis of the Wilms' tumor suppressor gene (WT1) in patients 46,XY disorders of sex development.
The Journal of clinical endocrinology and metabolism - 1 Jul 2011
Köhler B, Biebermann H, Friedsam V, Gellermann J, Maier R F, Pohl M, Wieacker P, Hiort O, Grüters A, Krude H
Abstract excerpt
CONTEXT: The Wilms' tumor suppressor gene (WT1) is one of the major regulators of early gonadal and kidney development. WT1 mutations have been identified in 46,XY disorders of sex development (DSD) with associated kidney disease and in few isolated forms of 46,XY DSD. OBJECTIVE: The objective of the study was the evaluation of WT1 mutations in different phenotypes of isolated 46,XY DSD and clinical consequences....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.