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Article

Diverse roles of host RNA binding proteins in RNA virus replication

1 Mar 2011

Abstract excerpt

Plus-strand +RNA viruses co-opt host RNA-binding proteins (RBPs) to perform many functions during viral replication. A few host RBPs have been identified that affect the recruitment of viral +RNAs for replication. Other subverted host RBPs help the assembly of the membrane-bound replicase complexes, regulate the activity of the replicase and control minus- or plus-strand RNA synthesis. The host RBPs also affect...

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PMID: 21505273
DOI: 10.4161/rna.8.2.15391

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