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Article

Molecular diagnostics for pharmacogenomic testing of fluoropyrimidine based-therapy: costs, methods and applications.

Clinical chemistry and laboratory medicine - 1 Jul 2011

Di Francia Raffaele, Berretta Massimiliano, Catapano Oriana, Canzoniero Lorella M T, Formisano Luigi

Abstract excerpt

Abstract Genetic testing of drug response represents an important goal for targeted therapy. In particular, 5-fluorouracil (5-FU) is the backbone of several chemotherapic protocols for treatment of solid tumors. Unfortunately, in some patients, 5-FU is toxic and causes gastrointestinal and hemato...

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Identifiers

PMID: 21504372
DOI: 10.1515/CCLM.2011.181

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21504372-2026-09-04.1. Manifest publication-graph-cohort-2026-09-04.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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