Article
No paradox, no progress: inverse cancer comorbidity in people with other complex diseases.
The Lancet. Oncology - 1 Jun 2011
Tabarés-Seisdedos Rafael, Dumont Nancy, Baudot Anaïs, Valderas Jose M, Climent Joan, Valencia Alfonso, Crespo-Facorro Benedicto, Vieta Eduard, Gómez-Beneyto Manuel, Martínez Salvador, Rubenstein John L
Abstract excerpt
In the past 5 years, several leading groups have attempted to explain why individuals with Down's syndrome have a reduced risk of many solid tumours and an increased risk of leukaemia and testicular cancer. Niels Bohr, the Danish physicist, noted that a paradox could initiate progress. We think that the paradox of a medical disorder protecting against cancer could be formalised in a new model of inverse cancer...
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