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Article

The self/nonself issue: A confrontation between proteomes

1 Jul 2010

Abstract excerpt

Defining self and nonself is the most compelling challenge in science today, at the basis of the numerous questions that remain unanswered in the immunology-pathology-therapy debate. The generation of the antibody repertoire, the complicated scenario offered by tolerance and autoimmunity, natural auto-antibodies and their relationship to autoimmune diseases, and positive and negative selection are only a few...

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Identifiers

PMID: 21487482
DOI: 10.4161/self.1.3.11897

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