Article
Design and characterization of genetically engineered zebrafish aquaporin-3 mutants highly permeable to the cryoprotectant ethylene glycol.
BMC biotechnology - 8 Apr 2011
Chauvigné François, Lubzens Esther, Cerdà Joan
Abstract excerpt
BACKGROUND: Increasing cell membrane permeability to water and cryoprotectants is critical for the successful cryopreservation of cells with large volumes. Artificial expression of water-selective aquaporins or aquaglyceroporins (GLPs), such as mammalian aquaporin-3 (AQP3), enhances cell permeability to water and cryoprotectants, but it is known that AQP3-mediated water and solute permeation is limited and pH...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
