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Article

Identification of a transforming MYB-GATA1 fusion gene in acute basophilic leukemia: a new entity in male infants

8 Apr 2011

Abstract excerpt

Acute basophilic leukemia (ABL) is a rare subtype of acute leukemia with clinical features and symptoms related to hyperhistaminemia because of excessive growth of basophils. No known recurrent cytogenetic abnormality is associated with this leukemia. Rare cases of t(X;6)(p11;q23) translocation have been described but these were sporadic. We report here 4 cases of ABL with a t(X;6)(p11;q23) translocation...

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PMID: 21474671
DOI: 10.1182/blood-2011-01-333013

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