Article
Calcium-dependent modulation and plasma membrane targeting of the AKT2 potassium channel by the CBL4/CIPK6 calcium sensor/protein kinase complex.
Cell research - 1 Jul 2011
Held Katrin, Pascaud François, Eckert Christian, Gajdanowicz Pawel, Hashimoto Kenji, Corratgé-Faillie Claire, Offenborn Jan Niklas, Lacombe Benoît, Dreyer Ingo, Thibaud Jean-Baptiste, Kudla Jörg
Abstract excerpt
Potassium (K(+)) channel function is fundamental to many physiological processes. However, components and mechanisms regulating the activity of plant K(+) channels remain poorly understood. Here, we show that the calcium (Ca(2+)) sensor CBL4 together with the interacting protein kinase CIPK6 modulates the activity and plasma membrane (PM) targeting of the K(+) channel AKT2 from Arabidopsis thaliana by mediating...
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